产品货号：
GS4484
中文名称：
重组人IL-22
英文名称：
Recombinant Human Interleukin-22
产品规格：
2μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 33.6kDa,non-disulfide-linked homodimeric protein containing of two 147 amino acid polypeptide chains.
储存条件：冷冻（-20℃）
概述
IL-22 is belonging to IL-10 family of regulatory cytokines which includes IL-10,IL-19,IL-20,IL-22,IL-24 and IL-26.Members of this family share partial homology in their amino acid sequences,but they are dissimilar in their biological functions.Produced by T lymphocytes and dendritic cells,IL-10 contributes to the inflammatory response in vivo.IL-22 signals through CRF2-4 and IL-22.It along with IL-17 is rapidly produced by splenic LTi-like cells and can be also produced by Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人IL-22，IL-22, Human，Recombinant Human Interleukin-22
储存条件：冷冻（-20℃）
概述
IL-22 is belonging to IL-10 family of regulatory cytokines which includes IL-10,IL-19,IL-20,IL-22,IL-24 and IL-26.Members of this family share partial homology in their amino acid sequences,but they are dissimilar in their biological functions.Produced by T lymphocytes and dendritic cells,IL-10 contributes to the inflammatory response in vivo.IL-22 signals through CRF2-4 and IL-22.It along with IL-17 is rapidly produced by splenic LTi-like cells and can be also produced by Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.3ng/ml,corresponding to a specific activity of>3.3×106 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 5.0. |
| 内毒素 | Less than 1 EU/μg of rHuIL-22 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI |
相关搜索：重组人IL-22，IL-22, Human，Recombinant Human Interleukin-22